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Efficacy and mechanism of combination of oxaliplatin with PKM2 knockdown in colorectal cancer

M2 isomer of pyruvate kinase (PKM2), a key enzyme in aerobic glycolysis, is closely related to cancer development and progression. Suppression of PKM2 exhibits synergistic effects with docetaxel in lung cancer, but the therapeutic potential in colorectal cancer (CRC) is unclear. The aim of the prese...

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Detalles Bibliográficos
Autores principales:	Yin, Chenxi, Lu, Wenhua, Ma, Mingzhe, Yang, Qiong, He, Wenzhuo, Hu, Yumin, Xia, Liangping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573921/ https://www.ncbi.nlm.nih.gov/pubmed/33093921 http://dx.doi.org/10.3892/ol.2020.12175

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