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Frequent birth-and-death events throughout perforin-1 evolution

BACKGROUND: Through its ability to open pores in cell membranes, perforin-1 plays a key role in the immune system. Consistent with this role, the gene encoding perforin shows hallmarks of complex evolutionary events, including amplification and pseudogenization, in multiple species. A large proporti...

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Detalles Bibliográficos
Autores principales: Araujo-Voces, Miguel, Quesada, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574235/
https://www.ncbi.nlm.nih.gov/pubmed/33076840
http://dx.doi.org/10.1186/s12862-020-01698-1