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Frequent birth-and-death events throughout perforin-1 evolution
BACKGROUND: Through its ability to open pores in cell membranes, perforin-1 plays a key role in the immune system. Consistent with this role, the gene encoding perforin shows hallmarks of complex evolutionary events, including amplification and pseudogenization, in multiple species. A large proporti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574235/ https://www.ncbi.nlm.nih.gov/pubmed/33076840 http://dx.doi.org/10.1186/s12862-020-01698-1 |