Progressive and accurate assembly of multi-domain protein structures from cryo-EM density maps

Progress in cryo-electron microscopy (cryo-EM) has provided the potential for large-size protein structure determination. However, the solution rate for multi-domain proteins remains low due to the difficulty in modeling inter-domain orientations. We developed DEMO-EM, an automatic method to assembl...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaogen, Li, Yang, Zhang, Chengxin, Zheng, Wei, Zhang, Guijun, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574260/
https://www.ncbi.nlm.nih.gov/pubmed/33083802
http://dx.doi.org/10.1101/2020.10.15.340455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574260/
https://www.ncbi.nlm.nih.gov/pubmed/33083802
http://dx.doi.org/10.1101/2020.10.15.340455

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