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Implementation of homology based and non-homology based computational methods for the identification and annotation of orphan enzymes: using Mycobacterium tuberculosis H37Rv as a case study

BACKGROUND: Homology based methods are one of the most important and widely used approaches for functional annotation of high-throughput microbial genome data. A major limitation of these methods is the absence of well-characterized sequences for certain functions. The non-homology methods based on...

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Detalles Bibliográficos
Autores principales: Sinha, Swati, Lynn, Andrew M., Desai, Dhwani K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574302/
https://www.ncbi.nlm.nih.gov/pubmed/33076816
http://dx.doi.org/10.1186/s12859-020-03794-x