Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous and complex disease, and treatments for this disease have not been curative for the majority of patients. In younger patients, internal tandem duplication of FLT3 (FLT3-ITD) is a common mutation for which two inhibitors (midostaurin and gilteritinib) w...

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Detalles Bibliográficos
Autores principales: Brinton, Lindsey T., Zhang, Pu, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Sher, Steven, Wasmuth, Ronni, Beaver, Larry, Cempre, Casey, Skinner, Jordan, Cannon, Matthew, Govande, Mukul, Harrington, Bonnie, Lehman, Amy, Byrd, John C., Lapalombella, Rosa, Blachly, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574303/
https://www.ncbi.nlm.nih.gov/pubmed/33076970
http://dx.doi.org/10.1186/s13045-020-00973-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574303/
https://www.ncbi.nlm.nih.gov/pubmed/33076970
http://dx.doi.org/10.1186/s13045-020-00973-4

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