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Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds

Recent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems. Yet critical to understanding whether tau propagation is relevant in pathophysiology of disease would be to learn if it alters neuronal propert...

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Detalles Bibliográficos
Autores principales: Perez-Rando, Marta, Dujardin, Simon, Bennett, Rachel E., Commins, Caitlin, Nibhanupudy, Tara, Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574323/
https://www.ncbi.nlm.nih.gov/pubmed/33076986
http://dx.doi.org/10.1186/s40478-020-01049-7