Cargando…
Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds
Recent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems. Yet critical to understanding whether tau propagation is relevant in pathophysiology of disease would be to learn if it alters neuronal propert...
Autores principales: | Perez-Rando, Marta, Dujardin, Simon, Bennett, Rachel E., Commins, Caitlin, Nibhanupudy, Tara, Hyman, Bradley T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574323/ https://www.ncbi.nlm.nih.gov/pubmed/33076986 http://dx.doi.org/10.1186/s40478-020-01049-7 |
Ejemplares similares
-
VCP suppresses proteopathic seeding in neurons
por: Zhu, Jiang, et al.
Publicado: (2022) -
Does proteopathic tau propagate trans-synaptically in the brain?
por: Hu, Wen, et al.
Publicado: (2022) -
Two simple assays for assessing the seeding activity of proteopathic tau
por: Liu, Fei, et al.
Publicado: (2023) -
Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons
por: Oakley, Derek H., et al.
Publicado: (2021) -
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation
por: Li, Longfei, et al.
Publicado: (2022)