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DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages
BACKGROUND: Dysfunction of the DNA methylation was associated with stem cell reprogramming. Moreover, DNA methyltransferase 1 (DNMT1) deficiency was involved in the differentiation of hair follicle stem cell (HFSc), but the molecular mechanisms remain unknown. METHODS: HFSc from human scalp tissues...
Autores principales: | Jin, Fangcao, Li, Min, Li, Xuyang, Zheng, Yunpeng, Zhang, Kun, Liu, Xiaojun, Cai, Bingjie, Yin, Guangwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574326/ https://www.ncbi.nlm.nih.gov/pubmed/33076979 http://dx.doi.org/10.1186/s13287-020-01864-8 |
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