Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas

IDH-mutant astrocytomas have a more indolent natural history and better prognosis than their IDH-wild type counterparts, but are still graded according to schemes developed prior to the recognition of this type of neoplasm as a distinct entity. Homozygous deletion of CDKN2A has been proposed as a mo...

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Detalles Bibliográficos
Autores principales: Marker, Daniel F., Pearce, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574334/
https://www.ncbi.nlm.nih.gov/pubmed/33081848
http://dx.doi.org/10.1186/s40478-020-01044-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574334/
https://www.ncbi.nlm.nih.gov/pubmed/33081848
http://dx.doi.org/10.1186/s40478-020-01044-y

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