Osteoporosis- and obesity-risk interrelationships: an epigenetic analysis of GWAS-derived SNPs at the developmental gene TBX15

A major challenge in translating findings from genome-wide association studies (GWAS) to biological mechanisms is pinpointing functional variants because only a very small percentage of variants associated with a given trait actually impact the trait. We used an extensive epigenetics, transcriptomic...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiao, Ehrlich, Kenneth C., Yu, Fangtang, Hu, Xiaojun, Meng, Xiang-He, Deng, Hong-Wen, Shen, Hui, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574382/
https://www.ncbi.nlm.nih.gov/pubmed/31975641
http://dx.doi.org/10.1080/15592294.2020.1716491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574382/
https://www.ncbi.nlm.nih.gov/pubmed/31975641
http://dx.doi.org/10.1080/15592294.2020.1716491

Ejemplares similares