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Osteoporosis- and obesity-risk interrelationships: an epigenetic analysis of GWAS-derived SNPs at the developmental gene TBX15
A major challenge in translating findings from genome-wide association studies (GWAS) to biological mechanisms is pinpointing functional variants because only a very small percentage of variants associated with a given trait actually impact the trait. We used an extensive epigenetics, transcriptomic...
Autores principales: | Zhang, Xiao, Ehrlich, Kenneth C., Yu, Fangtang, Hu, Xiaojun, Meng, Xiang-He, Deng, Hong-Wen, Shen, Hui, Ehrlich, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574382/ https://www.ncbi.nlm.nih.gov/pubmed/31975641 http://dx.doi.org/10.1080/15592294.2020.1716491 |
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