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FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels

BACKGROUND: FDG-PET hypermetabolism can be observed in mild cognitive impairment (MCI), but the link to primary pathologies of Alzheimer’s diseases (AD) including amyloid and tau is unclear. METHODS: Using voxel-based regression, we assessed local interactions between amyloid- and tau-PET on spatial...

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Detalles Bibliográficos
Autores principales: Rubinski, Anna, Franzmeier, Nicolai, Neitzel, Julia, Ewers, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574434/
https://www.ncbi.nlm.nih.gov/pubmed/33076977
http://dx.doi.org/10.1186/s13195-020-00702-6