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The specific distribution pattern of IKZF1 mutation in acute myeloid leukemia

IKZF1 belongs to the IKAROS family of transcription factors, and its deletion/mutation frequently affects acute lymphoblastic leukemia. In acute myeloid leukemia, IKZF1 deletion has been demonstrated recurrent, but whether IKZF1 mutation also exists in AML remained largely unknown. Herein, we analyz...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Zhang, Xuewu, Li, Xia, Lv, Yunfei, Zhu, Yanan, Wang, Jinghan, Jin, Jie, Yu, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574539/
https://www.ncbi.nlm.nih.gov/pubmed/33081843
http://dx.doi.org/10.1186/s13045-020-00972-5