Core regulatory circuitries in defining cancer cell identity across the malignant spectrum

Gene expression programmes driving cell identity are established by tightly regulated transcription factors that auto- and cross-regulate in a feed-forward manner, forming core regulatory circuitries (CRCs). CRC transcription factors create and engage super-enhancers by recruiting acetylation writer...

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Detalles Bibliográficos
Autores principales: Jahangiri, Leila, Tsaprouni, Loukia, Trigg, Ricky M., Williams, John A., Gkoutos, Georgios V., Turner, Suzanne D., Pereira, Joao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574545/
https://www.ncbi.nlm.nih.gov/pubmed/32634370
http://dx.doi.org/10.1098/rsob.200121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574545/
https://www.ncbi.nlm.nih.gov/pubmed/32634370
http://dx.doi.org/10.1098/rsob.200121

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