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BDNF Activates Postsynaptic TrkB Receptors to Induce Endocannabinoid Release and Inhibit Presynaptic Calcium Influx at a Calyx-Type Synapse

Brain-derived neurotropic factor (BDNF) has been shown to play critical roles in neural development, plasticity, and neurodegenerative diseases. The main function of BDNF in the brain is widely accepted to be synaptic regulation. However, how BDNF modulates synaptic transmission, especially the unde...

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Detalles Bibliográficos
Autores principales: Wu, Yichen, Liu, Qingzhuo, Guo, Bin, Ye, Fangfei, Ge, Jianlong, Xue, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574661/
https://www.ncbi.nlm.nih.gov/pubmed/32948677
http://dx.doi.org/10.1523/JNEUROSCI.2838-19.2020