Cargando…

In silico identification of Tretinoin as a SARS-CoV-2 envelope (E) protein ion channel inhibitor

Viroporins are oligomeric, pore forming, viral proteins that play critical roles in the life cycle of pathogenic viruses. Viroporins like HIV-1 Vpu, Alphavirus 6 K, Influenza M2, HCV p7, and Picornavirus 2B, form discrete aqueous passageways which mediate ion and small molecule transport in infected...

Descripción completa

Detalles Bibliográficos
Autores principales: Dey, Debajit, Borkotoky, Subhomoi, Banerjee, Manidipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574788/
https://www.ncbi.nlm.nih.gov/pubmed/33126128
http://dx.doi.org/10.1016/j.compbiomed.2020.104063