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In silico identification of Tretinoin as a SARS-CoV-2 envelope (E) protein ion channel inhibitor
Viroporins are oligomeric, pore forming, viral proteins that play critical roles in the life cycle of pathogenic viruses. Viroporins like HIV-1 Vpu, Alphavirus 6 K, Influenza M2, HCV p7, and Picornavirus 2B, form discrete aqueous passageways which mediate ion and small molecule transport in infected...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574788/ https://www.ncbi.nlm.nih.gov/pubmed/33126128 http://dx.doi.org/10.1016/j.compbiomed.2020.104063 |