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Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling

OBJECTIVES: Intracellular reactive oxygen species (ROS) induced by receptor activator of NF‐kB ligand (RANKL) has been proven to be a critical factor in the development of osteoclasts. This study aimed to prove that schisandrin A (Sch), a novel anti‐oxidant compound, is able to suppress osteoclastog...

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Detalles Bibliográficos
Autores principales: Ni, Shuo, Qian, Zhi, Yuan, Yin, Li, Dejian, Zhong, Zeyuan, Ghorbani, Farnaz, Zhang, Xu, Zhang, Fangxue, Zhang, Zhenhua, Liu, Zichen, Yu, Baoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574870/
https://www.ncbi.nlm.nih.gov/pubmed/32871020
http://dx.doi.org/10.1111/cpr.12882