Cargando…

Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling

OBJECTIVES: Intracellular reactive oxygen species (ROS) induced by receptor activator of NF‐kB ligand (RANKL) has been proven to be a critical factor in the development of osteoclasts. This study aimed to prove that schisandrin A (Sch), a novel anti‐oxidant compound, is able to suppress osteoclastog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ni, Shuo, Qian, Zhi, Yuan, Yin, Li, Dejian, Zhong, Zeyuan, Ghorbani, Farnaz, Zhang, Xu, Zhang, Fangxue, Zhang, Zhenhua, Liu, Zichen, Yu, Baoqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574870/ https://www.ncbi.nlm.nih.gov/pubmed/32871020 http://dx.doi.org/10.1111/cpr.12882

Ejemplares similares

Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis
por: Zhong, Zeyuan, et al.
Publicado: (2020)

Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL‐induced osteoclastogenesis
por: Qian, Zhi, et al.
Publicado: (2020)

Juglanin Inhibits Osteoclastogenesis in Ovariectomized Mice via the Suppression of NF-κB Signaling Pathways
por: Zhang, Fangxue, et al.
Publicado: (2021)

Finite element analysis of dual small plate fixation and single plate fixation for treatment of midshaft clavicle fractures
por: Zhang, Fangxue, et al.
Publicado: (2020)

Schisandrin B Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss
por: Wang, Jia, et al.
Publicado: (2020)

Injectable light-assisted thermo-responsive methylcellulose-sodium humate hydrogel proposed for photothermal ablation and localized delivery of cisplatin
por: Ghorbani, Farnaz, et al.
Publicado: (2022)

A novel degradable PCL/PLLA strapping band for internal fixation of fracture
por: Jin, Baoyan, et al.
Publicado: (2023)

Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 Signaling
por: Pan, Bin, et al.
Publicado: (2021)

Reduction of Aβ Generation by Schisandrin B through Restraining Beta-Secretase 1 Transcription and Translation
por: Li, Zeng, et al.
Publicado: (2018)

Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD
por: Zeng, Jiamin, et al.
Publicado: (2023)

The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption
por: Zhang, Chongjing, et al.
Publicado: (2022)

Schisandrin B elicits the Keap1-Nrf2 defense system via carbene reactive metabolite which is less harmful to mice liver
por: Feng, Shan, et al.
Publicado: (2018)

Schisandrin B for the treatment of male infertility
por: Zou, Di‐Xin, et al.
Publicado: (2021)

Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species
por: Ng, Andrew Ying Hui, et al.
Publicado: (2019)

Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcoma
por: Ni, Shuo, et al.
Publicado: (2020)

Schisandrin B attenuates CCl(4)-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways
por: Chen, Qingshan, et al.
Publicado: (2017)

Schisandrin B protects against angiotensin II-induced endotheliocyte deficits by targeting Keap1 and activating Nrf2 pathway
por: Han, Jibo, et al.
Publicado: (2018)

A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity
por: Chen, Yueqi, et al.
Publicado: (2020)

Schisandrin B regulates lipid metabolism in subcutaneous adipocytes
por: Kwan, Hiu Yee, et al.
Publicado: (2017)

Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation
por: Guo, Wen, et al.
Publicado: (2021)

Reactive Oxygen Species and Nrf2: Functional and Transcriptional Regulators of Hematopoiesis
por: Hu, Linping, et al.
Publicado: (2019)

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H(2)O(2) accumulation
por: Bartell, Shoshana M., et al.
Publicado: (2014)

Schisandrin B Attenuates Airway Inflammation by Regulating the NF-κB/Nrf2 Signaling Pathway in Mouse Models of Asthma
por: Chen, Yaqin, et al.
Publicado: (2021)

NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors
por: Zhong, Zeyuan, et al.
Publicado: (2023)

Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome
por: Zhang, Weiwei, et al.
Publicado: (2021)

Differential Action between Schisandrin A and Schisandrin B in Eliciting an Anti-Inflammatory Action: The Depletion of Reduced Glutathione and the Induction of an Antioxidant Response
por: Leong, Pou Kuan, et al.
Publicado: (2016)

Therapeutic effect of Schisandrin A on avian colibacillosis through gut-liver axis
por: Bao, Jialu, et al.
Publicado: (2021)

Cytochrome P-450-catalyzed reactive oxygen species production mediates the (–)schisandrin B-induced glutathione and heat shock responses in H9c2 cardiomyocytes
por: Chen, Na, et al.
Publicado: (2012)

Alliin Attenuated RANKL-Induced Osteoclastogenesis by Scavenging Reactive Oxygen Species through Inhibiting Nox1
por: Chen, Yueqi, et al.
Publicado: (2016)

Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species
por: Chen, Kai, et al.
Publicado: (2019)

Isorhamnetin attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through modulating reactive oxygen species homeostasis
por: Zhou, Feng, et al.
Publicado: (2019)

The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species
por: Zhang, Lun, et al.
Publicado: (2016)

Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1
por: Kang, Hui, et al.
Publicado: (2016)

NRF2 Is an Upstream Regulator of MYC-Mediated Osteoclastogenesis and Pathological Bone Erosion
por: Park, Peter Sang Uk, et al.
Publicado: (2020)

Fucoxanthin Suppresses Osteoclastogenesis via Modulation of MAP Kinase and Nrf2 Signaling
por: Ha, You-Jung, et al.
Publicado: (2021)

Aggregation-Induced Generation of Reactive Oxygen Species: Mechanism and Photosensitizer Construction
por: Ni, Juechen, et al.
Publicado: (2021)

Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity
por: Zhang, Yi, et al.
Publicado: (2015)

Bach1 Inhibition Suppresses Osteoclastogenesis via Reduction of the Signaling via Reactive Oxygen Species by Reinforced Antioxidation
por: Wada, Satoshi, et al.
Publicado: (2020)

Antiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells
por: Li, Qun, et al.
Publicado: (2015)

Role of C-reactive protein in osteoclastogenesis in rheumatoid arthritis
por: Kim, Kyoung-Woon, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vquea8akkmm5r6vt7v1hoq7brs