Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease

OBJECTIVES: Huntington's disease (HD) is a devastating neurodegenerative disease caused by polyglutamine (polyQ) expansion in the huntingtin (HTT) gene. Mutant huntingtin (mHTT) is the main cause of HD and is associated with impaired mitochondrial dynamics, ubiquitin‐proteasome system and autop...

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Detalles Bibliográficos
Autores principales: Li, Endan, Park, Hee Ra, Hong, Chang Pyo, Kim, Younghoon, Choi, Jiwoo, Lee, Suji, Park, Hyun Jung, Lee, Bomi, Kim, Tae Aug, Kim, Seong Jin, Kim, Hyun Sook, Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574873/
https://www.ncbi.nlm.nih.gov/pubmed/32865873
http://dx.doi.org/10.1111/cpr.12893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574873/
https://www.ncbi.nlm.nih.gov/pubmed/32865873
http://dx.doi.org/10.1111/cpr.12893

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