IL2RG‐deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma‐derived tumours

OBJECTIVES: Immunodeficient mice injected with human cancer cell lines have been used for human oncology studies and anti‐cancer drug trials for several decades. However, rodents are not ideal species for modelling human cancer because rodents are physiologically dissimilar to humans. Therefore, ant...

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Detalles Bibliográficos
Autores principales: Ren, Jilong, Yu, Dawei, Fu, Rui, An, Peipei, Sun, Renren, Wang, Zhengzhu, Guo, Runfa, Li, Haoyun, Zhang, Ying, Li, Ziyi, Yang, Yong‐Guang, Li, Wei, Hai, Tang, Hu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Brief Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574875/
https://www.ncbi.nlm.nih.gov/pubmed/32871045
http://dx.doi.org/10.1111/cpr.12863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574875/
https://www.ncbi.nlm.nih.gov/pubmed/32871045
http://dx.doi.org/10.1111/cpr.12863

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