Interleukin‐4‐loaded hydrogel scaffold regulates macrophages polarization to promote bone mesenchymal stem cells osteogenic differentiation via TGF‐β1/Smad pathway for repair of bone defect

OBJECTIVE: Tissue engineering is a promising strategy for repair of large bone defect. However, the immune system reactions to biological scaffold are increasingly being recognized as a crucial factor influencing regeneration efficacy. In this study, a bone‐bioactive hydrogel bead loaded with interl...

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Detalles Bibliográficos
Autores principales: Zhang, Jiankang, Shi, Haitao, Zhang, Nian, Hu, Liru, Jing, Wei, Pan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574882/
https://www.ncbi.nlm.nih.gov/pubmed/32951298
http://dx.doi.org/10.1111/cpr.12907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574882/
https://www.ncbi.nlm.nih.gov/pubmed/32951298
http://dx.doi.org/10.1111/cpr.12907

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