3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice

Pathogenic coronaviruses are a major threat to global public health, as exemplified by severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the newly emerged SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19). We d...

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Detalles Bibliográficos
Autores principales: Rathnayake, Athri D., Zheng, Jian, Kim, Yunjeong, Perera, Krishani Dinali, Mackin, Samantha, Meyerholz, David K., Kashipathy, Maithri M., Battaile, Kevin P., Lovell, Scott, Perlman, Stanley, Groutas, William C., Chang, Kyeong-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574915/
https://www.ncbi.nlm.nih.gov/pubmed/32747425
http://dx.doi.org/10.1126/scitranslmed.abc5332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574915/
https://www.ncbi.nlm.nih.gov/pubmed/32747425
http://dx.doi.org/10.1126/scitranslmed.abc5332

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