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The Vitamin D Receptor in Osteoblast-Lineage Cells Is Essential for the Proresorptive Activity of 1α,25(OH)(2)D(3) In Vivo

We previously reported that daily administration of a pharmacological dose of eldecalcitol, an analog of 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)], increased bone mass by suppressing bone resorption. These antiresorptive effects were found to be mediated by the vitamin D receptor (VDR) in osteo...

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Detalles Bibliográficos
Autores principales: Mori, Tomoki, Horibe, Kanji, Koide, Masanori, Uehara, Shunsuke, Yamamoto, Yoko, Kato, Shigeaki, Yasuda, Hisataka, Takahashi, Naoyuki, Udagawa, Nobuyuki, Nakamichi, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575053/
https://www.ncbi.nlm.nih.gov/pubmed/32987399
http://dx.doi.org/10.1210/endocr/bqaa178