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MDM2-P53 Signaling Pathway-Mediated Upregulation of CDC20 Promotes Progression of Human Diffuse Large B-Cell Lymphoma

BACKGROUND: Cell-division cycle 20 (CDC20) is overexpressed in a variety of tumor cells and is negatively regulated by wild-type p53 (wtp53). Our previous study uncovered that CDC20 was upregulated and associated with poor outcome in diffuse large B-cell lymphoma (DLBCL) based on bioinformatics anal...

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Detalles Bibliográficos
Autores principales: Sun, Chengtao, Li, Mengzhen, Feng, Yanfen, Sun, Feifei, Zhang, Li, Xu, Yanjie, Lu, Suying, Zhu, Jia, Huang, Junting, Wang, Juan, Hu, Yang, Zhang, Yizhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575066/
https://www.ncbi.nlm.nih.gov/pubmed/33116627
http://dx.doi.org/10.2147/OTT.S253758