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Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection

The ribonucleocapsid complex of respiratory syncytial virus (RSV) is responsible for both viral mRNA transcription and viral replication during infection, though little is known about how this dual function is achieved. Here, we report the use of a recombinant RSV virus with a FLAG-tagged large poly...

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Detalles Bibliográficos
Autores principales: Blanchard, Emmeline L., Braun, Molly R., Lifland, Aaron W., Ludeke, Barbara, Noton, Sarah L., Vanover, Daryll, Zurla, Chiara, Fearns, Rachel, Santangelo, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575074/
https://www.ncbi.nlm.nih.gov/pubmed/33031461
http://dx.doi.org/10.1371/journal.ppat.1008987