Cargando…
Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection
The ribonucleocapsid complex of respiratory syncytial virus (RSV) is responsible for both viral mRNA transcription and viral replication during infection, though little is known about how this dual function is achieved. Here, we report the use of a recombinant RSV virus with a FLAG-tagged large poly...
Autores principales: | Blanchard, Emmeline L., Braun, Molly R., Lifland, Aaron W., Ludeke, Barbara, Noton, Sarah L., Vanover, Daryll, Zurla, Chiara, Fearns, Rachel, Santangelo, Philip J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575074/ https://www.ncbi.nlm.nih.gov/pubmed/33031461 http://dx.doi.org/10.1371/journal.ppat.1008987 |
Ejemplares similares
-
RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane
por: Vanover, Daryll, et al.
Publicado: (2017) -
Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection
por: Tiwari, Pooja Munnilal, et al.
Publicado: (2018) -
Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts
por: Braun, Molly R., et al.
Publicado: (2021) -
Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA
por: Blanchard, Emmeline L., et al.
Publicado: (2018) -
RNA elongation by respiratory syncytial virus polymerase is calibrated by conserved region V
por: Braun, Molly R., et al.
Publicado: (2017)