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Temporal Pole Responds to Subtle Changes in Local Thyroid Hormone Signaling

To study thyroid hormone (TH) signaling in the human brain, we analyzed published microarray data sets of the temporal pole (Brodmann area 38) of 19 deceased donors. An index of TH signaling built on the expression of 19 well known TH-responsive genes in mouse brains (T3S+) varied from 0.92 to 1.1....

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Detalles Bibliográficos
Autores principales: Marcelino, Cícera P, McAninch, Elizabeth A, Fernandes, Gustavo W, Bocco, Barbara M L C, Ribeiro, Miriam O, Bianco, Antonio C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575126/
https://www.ncbi.nlm.nih.gov/pubmed/33123655
http://dx.doi.org/10.1210/jendso/bvaa136