Luminespib counteracts the Kifunensine-induced lung endothelial barrier dysfunction

Unfolded protein response (UPR) suppression by Kifunensine has been associated with lung hyperpermeability, the hallmark of Acute Respiratory Distress Syndrome. The present study investigates the effects of the heat shock protein 90 inhibitor Luminespib (AUY-922) towards the Kifunensine-triggered lu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubra, Khadeja-Tul, Uddin, Mohammad A., Akhter, Mohammad S., Barabutis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575137/
https://www.ncbi.nlm.nih.gov/pubmed/33094291
http://dx.doi.org/10.1016/j.crtox.2020.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575137/
https://www.ncbi.nlm.nih.gov/pubmed/33094291
http://dx.doi.org/10.1016/j.crtox.2020.09.003

Ejemplares similares