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Luminespib counteracts the Kifunensine-induced lung endothelial barrier dysfunction
Unfolded protein response (UPR) suppression by Kifunensine has been associated with lung hyperpermeability, the hallmark of Acute Respiratory Distress Syndrome. The present study investigates the effects of the heat shock protein 90 inhibitor Luminespib (AUY-922) towards the Kifunensine-triggered lu...
Autores principales: | Kubra, Khadeja-Tul, Uddin, Mohammad A., Akhter, Mohammad S., Barabutis, Nektarios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575137/ https://www.ncbi.nlm.nih.gov/pubmed/33094291 http://dx.doi.org/10.1016/j.crtox.2020.09.003 |
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