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Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain

Neurons communicate by the activity-dependent release of small-molecule neurotransmitters packaged into synaptic vesicles (SVs). Although many molecules have been identified as neurotransmitters, technical limitations have precluded a full metabolomic analysis of SV content. Here, we present a workf...

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Detalles Bibliográficos
Autores principales: Chantranupong, Lynne, Saulnier, Jessica L, Wang, Wengang, Jones, Drew R, Pacold, Michael E, Sabatini, Bernardo L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575323/
https://www.ncbi.nlm.nih.gov/pubmed/33043885
http://dx.doi.org/10.7554/eLife.59699