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Treatment of malignant peripheral nerve sheath tumors in pediatric NF1 disease

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare yet highly aggressive soft tissue sarcomas. Children with neurofibromatosis type 1 (NF1) have a 10% lifetime risk for development of MPNST. Prognosis remains poor and survival seems worse for NF1 patients. METHODS: This narrative...

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Detalles Bibliográficos
Autores principales: Martin, Enrico, Flucke, Uta E., Coert, J. Henk, van Noesel, Max M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575473/
https://www.ncbi.nlm.nih.gov/pubmed/32494969
http://dx.doi.org/10.1007/s00381-020-04687-3