Neuron type-specific expression of a mutant KRAS impairs hippocampal-dependent learning and memory

KRAS mutations are associated with rare cases of neurodevelopmental disorders that can cause intellectual disabilities. Previous studies showed that mice expressing a mutant KRAS have impaired the development and function of GABAergic inhibitory neurons, which may contribute to behavioural deficits...

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Detalles Bibliográficos
Autores principales: Ryu, Hyun-Hee, Kang, Minkyung, Hwang, Kyoung-Doo, Jang, Han Byul, Kim, Sang Jeong, Lee, Yong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575532/
https://www.ncbi.nlm.nih.gov/pubmed/33082413
http://dx.doi.org/10.1038/s41598-020-74610-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575532/
https://www.ncbi.nlm.nih.gov/pubmed/33082413
http://dx.doi.org/10.1038/s41598-020-74610-y

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