Synthesis of an acyl-acyl carrier protein synthetase inhibitor to study fatty acid recycling

Fatty acids are essential to most organisms and are made endogenously by the fatty acid synthase (FAS). FAS is an attractive target for antibiotics and many inhibitors are in clinical development. However, some gram-negative bacteria harbor an enzyme known as the acyl-acyl carrier protein synthetase...

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Detalles Bibliográficos
Autores principales: Currie, Madeline F., Persaud, Dylan M., Rana, Niralee K., Platt, Amanda J., Beld, Joris, Jaremko, Kara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575536/
https://www.ncbi.nlm.nih.gov/pubmed/33082446
http://dx.doi.org/10.1038/s41598-020-74731-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575536/
https://www.ncbi.nlm.nih.gov/pubmed/33082446
http://dx.doi.org/10.1038/s41598-020-74731-4

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