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Synthesis of an acyl-acyl carrier protein synthetase inhibitor to study fatty acid recycling
Fatty acids are essential to most organisms and are made endogenously by the fatty acid synthase (FAS). FAS is an attractive target for antibiotics and many inhibitors are in clinical development. However, some gram-negative bacteria harbor an enzyme known as the acyl-acyl carrier protein synthetase...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575536/ https://www.ncbi.nlm.nih.gov/pubmed/33082446 http://dx.doi.org/10.1038/s41598-020-74731-4 |