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Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling

Cardiac growth and remodelling are key biological processes influencing the physiological performance of the heart, and a previous study showed a critical role for intracellular HMGB1 in vitro. However, the in vivo study, which used conditional Hmgb1 ablation, did not show a significant effect on ce...

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Detalles Bibliográficos
Autores principales: Yu, Peng, Liu, Ming, Zhang, Baoli, Yu, Ying, Su, Enyong, Xie, Shiyao, Zhang, Lei, Yang, Xue, Jiang, Hong, Chen, Ruizhen, Zou, Yunzeng, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575537/
https://www.ncbi.nlm.nih.gov/pubmed/33101708
http://dx.doi.org/10.1038/s41420-020-00340-9