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Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network

The ventricular conduction system coordinates heartbeats by rapid propagation of electrical activity through the Purkinje fiber (PF) network. PFs share common progenitors with contractile cardiomyocytes, yet the mechanisms of segregation and network morphogenesis are poorly understood. Here, we appl...

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Detalles Bibliográficos
Autores principales: Choquet, Caroline, Kelly, Robert G., Miquerol, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575572/
https://www.ncbi.nlm.nih.gov/pubmed/33082351
http://dx.doi.org/10.1038/s41467-020-19150-9