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Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation
Our previous studies have reported that RFPL3 protein exerts its unique function as a transcriptional factor of hTERT promoter after being transported into the lung cancer cell nucleus. However, the detailed mechanism by which RFPL3 undergoes nuclear transport has not been reported yet. Here, we ide...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575581/ https://www.ncbi.nlm.nih.gov/pubmed/33082305 http://dx.doi.org/10.1038/s41419-020-03101-9 |