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Importin 13 promotes NSCLC progression by mediating RFPL3 nuclear translocation and hTERT expression upregulation

Our previous studies have reported that RFPL3 protein exerts its unique function as a transcriptional factor of hTERT promoter after being transported into the lung cancer cell nucleus. However, the detailed mechanism by which RFPL3 undergoes nuclear transport has not been reported yet. Here, we ide...

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Detalles Bibliográficos
Autores principales: Zohud, Bisan Abdalfatah, Guo, Ping, Zohud, Batoul Abdalfatah, Li, Fengzhou, Hao, Jiao J., Shan, Xiu, Yu, Wendan, Guo, Wei, Qin, Yu, Cai, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575581/
https://www.ncbi.nlm.nih.gov/pubmed/33082305
http://dx.doi.org/10.1038/s41419-020-03101-9