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WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasive strategies. We show here that high Myosin II activity, high levels of ki-67 and high tumour-initiating abilities are characteristic of invasive amo...

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Detalles Bibliográficos
Autores principales: Rodriguez-Hernandez, Irene, Maiques, Oscar, Kohlhammer, Leonie, Cantelli, Gaia, Perdrix-Rosell, Anna, Monger, Joanne, Fanshawe, Bruce, Bridgeman, Victoria L., Karagiannis, Sophia N., Penin, Rosa M., Marcolval, Joaquim, Marti, Rosa M., Matias-Guiu, Xavier, Fruhwirth, Gilbert O., Orgaz, Jose L., Malanchi, Ilaria, Sanz-Moreno, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575593/
https://www.ncbi.nlm.nih.gov/pubmed/33082334
http://dx.doi.org/10.1038/s41467-020-18951-2