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The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity

During tumorigenesis, cancer cells are exposed to a wide variety of intrinsic and extrinsic stresses that challenge homeostasis and growth. Cancer cells display activation of distinct mechanisms for adaptation and growth even in the presence of stress. Autophagy is a catabolic mechanism that aides i...

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Detalles Bibliográficos
Autores principales: Chavez-Dominguez, Rodolfo, Perez-Medina, Mario, Lopez-Gonzalez, Jose S., Galicia-Velasco, Miriam, Aguilar-Cazares, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575731/
https://www.ncbi.nlm.nih.gov/pubmed/33117715
http://dx.doi.org/10.3389/fonc.2020.578418