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The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity
During tumorigenesis, cancer cells are exposed to a wide variety of intrinsic and extrinsic stresses that challenge homeostasis and growth. Cancer cells display activation of distinct mechanisms for adaptation and growth even in the presence of stress. Autophagy is a catabolic mechanism that aides i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575731/ https://www.ncbi.nlm.nih.gov/pubmed/33117715 http://dx.doi.org/10.3389/fonc.2020.578418 |