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Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure

Nicotine acts as a potent modulator of normal cellular responses through the nicotinic acetylcholine receptor subtype alpha7. In a mouse genetic model of alpha7 receptor dysfunction, alpha7(E260A:G), 85 percent of 18 month-old mice exhibit an age-associated spontaneous loosening or complete loss of...

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Detalles Bibliográficos
Autores principales: Rogers, Scott W., Myers, Elizabeth J., Gahring, Lorise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575759/
https://www.ncbi.nlm.nih.gov/pubmed/33117372
http://dx.doi.org/10.3389/fimmu.2020.575200