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Sonic Hedgehog Signaling in Cranial Neural Crest Cells Regulates Microvascular Morphogenesis in Facial Development

Sonic hedgehog (Shh) pathway disruption causes craniofacial malformations including orofacial clefts (OFCs) of the lip and palate. In normal craniofacial morphogenesis, Shh signals to multipotent cranial neural crest cells (cNCCs) and was recently discovered to regulate the angiogenic transcriptome,...

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Detalles Bibliográficos
Autores principales: Sun, Miranda R., Chung, Hannah M., Matsuk, Veronika, Fink, Dustin M., Stebbins, Matthew J., Palecek, Sean P., Shusta, Eric V., Lipinski, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575766/
https://www.ncbi.nlm.nih.gov/pubmed/33117819
http://dx.doi.org/10.3389/fcell.2020.590539