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HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats

Obstructive sleep apnea, similar to intermittent hypoxia (IH) during sleep, is associated with laryngeal airway hyperreactivity (LAH). IH-induced laryngeal oxidative stress may contribute to LAH, but the underlying mechanism remains unknown. Conscious rats were subjected to repetitive 75 s cycles of...

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Detalles Bibliográficos
Autores principales: Lin, You Shuei, Shen, Yan-Jhih, Ou, Ping-Hsun, Lai, Ching Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575773/
https://www.ncbi.nlm.nih.gov/pubmed/33117193
http://dx.doi.org/10.3389/fphys.2020.575260