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The Genome in a Three-Dimensional Context: Deciphering the Contribution of Noncoding Mutations at Enhancers to Blood Cancer

Associations between blood cancer and genetic predisposition, including both inherited variants and acquired mutations and epimutations, have been well characterized. However, the majority of these variants affect noncoding regions, making their mechanisms difficult to hypothesize and hindering the...

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Detalles Bibliográficos
Autores principales: Rovirosa, Llorenç, Ramos-Morales, Alberto, Javierre, Biola M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575776/
https://www.ncbi.nlm.nih.gov/pubmed/33117405
http://dx.doi.org/10.3389/fimmu.2020.592087