Diclofenac impairs autophagic flux via oxidative stress and lysosomal dysfunction: Implications for hepatotoxicity

Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with various side effects, including cardiovascular and hepatic disorders. Studies suggest that mitochondrial damage and oxidative stress are important mediators of toxicity, yet the underlying mechanisms are poorly understoo...

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Detalles Bibliográficos
Autores principales: Jung, Seung-Hwan, Lee, Wonseok, Park, Seung-Hyun, Lee, Kang-Yo, Choi, You-Jin, Choi, Soohee, Kang, Dongmin, Kim, Sinri, Chang, Tong-Shin, Hong, Soon-Sun, Lee, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575798/
https://www.ncbi.nlm.nih.gov/pubmed/33080439
http://dx.doi.org/10.1016/j.redox.2020.101751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575798/
https://www.ncbi.nlm.nih.gov/pubmed/33080439
http://dx.doi.org/10.1016/j.redox.2020.101751

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