Design and synthesis of coumarin-triazole hybrids: biocompatible anti-diabetic agents, in silico molecular docking and ADME screening

The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (a-e) in four steps starting from substituted salicylaldehyde 1 (a-e), and diethyl malonate 2. The spectroscopic studies provide the structure proofs of the new compounds, and the molecular structure of an intermediate 3a by...

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Detalles Bibliográficos
Autores principales: Channa Basappa, Vagish, Hamse Kameshwar, Vivek, Kumara, Karthik, Achutha, Dileep Kumar, Neratur Krishnappagowda, Lokanath, Kariyappa, Ajay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575805/
https://www.ncbi.nlm.nih.gov/pubmed/33102875
http://dx.doi.org/10.1016/j.heliyon.2020.e05290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575805/
https://www.ncbi.nlm.nih.gov/pubmed/33102875
http://dx.doi.org/10.1016/j.heliyon.2020.e05290

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