Cargando…

Metabolome Changes during In Vivo Red Cell Aging Reveal Disruption of Key Metabolic Pathways

Understanding the mechanisms for cellular aging is a fundamental question in biology. Normal red blood cells (RBCs) survive for approximately 100 days, and their survival is likely limited by functional decline secondary to cumulative damage to cell constituents, which may be reflected in altered me...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamshidi, Neema, Xu, Xiuling, von Löhneysen, Katharina, Soldau, Katrin, Mohney, Rob P., Karoly, Edward D., Scott, Mike, Friedman, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575880/
https://www.ncbi.nlm.nih.gov/pubmed/33103072
http://dx.doi.org/10.1016/j.isci.2020.101630