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Metabolome Changes during In Vivo Red Cell Aging Reveal Disruption of Key Metabolic Pathways
Understanding the mechanisms for cellular aging is a fundamental question in biology. Normal red blood cells (RBCs) survive for approximately 100 days, and their survival is likely limited by functional decline secondary to cumulative damage to cell constituents, which may be reflected in altered me...
Autores principales: | Jamshidi, Neema, Xu, Xiuling, von Löhneysen, Katharina, Soldau, Katrin, Mohney, Rob P., Karoly, Edward D., Scott, Mike, Friedman, Jeffrey S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575880/ https://www.ncbi.nlm.nih.gov/pubmed/33103072 http://dx.doi.org/10.1016/j.isci.2020.101630 |
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