Downregulation of Keap1 Confers Features of a Fasted Metabolic State

Transcription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) and its main negative regulator, Kelch-like ECH-associated protein 1 (Keap1), are at the interface between redox and intermediary metabolism, allowing adaptation and survival under conditions of oxidative, inflammatory, and...

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Detalles Bibliográficos
Autores principales: Knatko, Elena V., Tatham, Michael H., Zhang, Ying, Castro, Cecilia, Higgins, Maureen, Dayalan Naidu, Sharadha, Leonardi, Chiara, de la Vega, Laureano, Honda, Tadashi, Griffin, Julian L., Hay, Ronald T., Dinkova-Kostova, Albena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575887/
https://www.ncbi.nlm.nih.gov/pubmed/33103077
http://dx.doi.org/10.1016/j.isci.2020.101638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575887/
https://www.ncbi.nlm.nih.gov/pubmed/33103077
http://dx.doi.org/10.1016/j.isci.2020.101638

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