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Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment

Hypoxia (Hx) is a component of multiple disorders, including stroke and sleep-disordered breathing, which often precede or are comorbid with neurodegenerative diseases. However, little is known about how hypoxia affects the ability of microglia, resident CNS macrophages, to respond to subsequent inf...

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Detalles Bibliográficos
Autores principales: Kiernan, Elizabeth A., Ewald, Andrea C., Ouellette, Jonathan N., Wang, Tao, Agbeh, Abiye, Knutson, Andrew O., Roopra, Avtar S., Watters, Jyoti J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575929/
https://www.ncbi.nlm.nih.gov/pubmed/33132843
http://dx.doi.org/10.3389/fncel.2020.535549