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Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging

We describe here the design and implementation of an in vitro microvascular open model system using human brain microvascular endothelial cells. The design has several advantages over other traditional closed microfluidic platforms: (1) it enables controlled unidirectional flow of media at physiolog...

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Detalles Bibliográficos
Autores principales: Salman, Mootaz M., Marsh, Graham, Kusters, Ilja, Delincé, Matthieu, Di Caprio, Giuseppe, Upadhyayula, Srigokul, de Nola, Giovanni, Hunt, Ronan, Ohashi, Kazuka G., Gray, Taylor, Shimizu, Fumitaka, Sano, Yasuteru, Kanda, Takashi, Obermeier, Birgit, Kirchhausen, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576009/
https://www.ncbi.nlm.nih.gov/pubmed/33117784
http://dx.doi.org/10.3389/fbioe.2020.573775